Author

I. Donaldson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Mullan· 1 shared A. P. Gilmore· 1 shared A. Ucar· 1 shared B. A. Telfer· 1 shared C. Williams· 1 shared D. Novo· 1 shared E. Camacho· 1 shared E. Jokl· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Mullan

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

HER2 overexpression initiates breast tumorigenesis non-cell-autonomously by inducing oxidative stress in the tissue microenvironment

S. B. Gurler, O. Wagstaff, L. Dimitrova, F. Chen, R. Pedley, W. Weston, I. Donaldson, B. A. Telfer, D. Novo, K. Pavlou, G. Taylor, Y. Ou, K. J. Williams, A. P. Gilmore, K. Brennan, A. Ucar

This study shows HER2 overexpression drives breast tumorigenesis by inducing oxidative stress in the tissue microenvironment, not directly in cancer stem cells.

bioRxiv · Aug 25, 2023 · PreprintCancer Biology

PAK1-dependant mechanotransduction enables myofibroblast nuclear adaptation and chromatin organisation during fibrosis

E. Jokl, A. Mullan, K. Simpson, L. Birchall, L. Pearmain, K. Martin, J. Pritchett, R. Shah, N. Hodson, C. Williams, E. Camacho, L. Zeef, I. Donaldson, V. Athwal, N. Hanley, K. Piper Hanley

The paper identifies PAK1-dependent mechanotransduction as critical for myofibroblast nuclear adaptation and chromatin organization during fibrosis, showing its impact on gene regulation and disease progression.

bioRxiv · Mar 31, 2023 · PreprintCell Biology