Author

B. A. Telfer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

K. J. Williams· 2 shared A. F. L. Hurlstone· 1 shared A. P. Gilmore· 1 shared A. Ucar· 1 shared C. Evangelou· 1 shared C. W. Wong· 1 shared D. J. Wilcock· 1 shared D. Novo· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

K. J. Williams

Mutual co-authors in cluster

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2 papers

Recent·Most cited

PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven adaptive resistance

C. W. Wong, C. Evangelou, K. N. Sefton, R. Leshem, K. Sergiou, M. L. Fernandez Carro, E. Uzuner, H. Mole, B. A. Telfer, D. J. Wilcock, M. P. Smith, K. Kunii, N. R. Perl, P. Lorigan, K. J. Williams, , A. F. L. Hurlstone

This study shows that PARP14 inhibition restores PD-1 checkpoint inhibitor response in IFNγ-resistant tumors by increasing T cell infiltration and reducing regulatory T cells.

Nature Communications · Sep 26, 2023Peer-reviewedCancer Biology

HER2 overexpression initiates breast tumorigenesis non-cell-autonomously by inducing oxidative stress in the tissue microenvironment

S. B. Gurler, O. Wagstaff, L. Dimitrova, F. Chen, R. Pedley, W. Weston, I. Donaldson, B. A. Telfer, D. Novo, K. Pavlou, G. Taylor, Y. Ou, K. J. Williams, A. P. Gilmore, K. Brennan, A. Ucar

This study shows HER2 overexpression drives breast tumorigenesis by inducing oxidative stress in the tissue microenvironment, not directly in cancer stem cells.

bioRxiv · Aug 25, 2023 · PreprintCancer Biology