Viral capsid, antibody, and receptor interactions: experimental analysis of the antibody escape evolution of canine parvovirus
R. Lopez-Astacio, O. F. Adu, D. J. Goetschius…·C. R. Parrish
This study uses in vitro selection and deep sequencing to identify escape mutations in canine parvovirus selected by two antibodies, revealing mechanisms of antibody and receptor binding interactions.