Author

B. R. Wasik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Organism:human· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

C. R. Parrish· 6 shared E. C. Holmes· 4 shared K. N. Barnard· 4 shared W. Weichert· 4 shared I. E. H. Voorhees· 3 shared B. K. Alford-Lawrence· 2 shared B. K. Lawrence· 2 shared J. R. LaClair· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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6 shared papersMicrobiology

C. R. Parrish

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Viral capsid, antibody, and receptor interactions: experimental analysis of the antibody escape evolution of canine parvovirus

R. Lopez-Astacio, O. F. Adu, D. J. Goetschius, H. Lee, W. Weichert, B. R. Wasik, S. P. Frueh, B. K. Alford, I. E. H. Voorhees, J. F. Flint, S. Saddoris, L. B. Goodman, E. C. Holmes, S. Hafenstein, C. R. Parrish

This study uses in vitro selection and deep sequencing to identify escape mutations in canine parvovirus selected by two antibodies, revealing mechanisms of antibody and receptor binding interactions.

Journal of Virology · Jun 29, 2023Peer-reviewedEvolutionary Biology

Understanding the Divergent Evolution and Epidemiology of H3N8 Influenza Viruses in Dogs and Horses

B. R. Wasik, E. Rothschild, I. E. Voorhees, S. E. Reedy, P. R. Murcia, N. Pusterla, T. M. Chambers, L. B. Goodman, J. C. Kile, E. C. Holmes, C. R. Parrish

This paper compares the evolution and epidemiology of H3N8 influenza viruses in dogs and horses to understand their distinct evolutionary fates and potential zoonotic risks.

bioRxiv · Mar 22, 2023 · PreprintEvolutionary Biology

Influenza A viruses serially passaged in different MDCK cell lines exhibit limited sequence variation across their genomes, with the exception of the hemagglutinin gene

K. N. Barnard, B. R. Wasik, B. K. Alford-Lawrence, J. J. Hayward, W. Weichert, I. E. H. Voorhees, E. C. Holmes, C. R. Parrish

This study passaged influenza A viruses in different MDCK cell lines and found limited genome-wide sequence variation, with most mutations occurring in the hemagglutinin gene.

bioRxiv · Feb 20, 2020 · PreprintMicrobiology

The effects of modified sialic acids on mucus and erythrocytes on influenza A virus HA and NA functions

K. N. Barnard, B. K. Alford-Lawrence, D. W. Buchholz, B. R. Wasik, J. R. LaClair, H. Yu, R. Honce, S. Ruhl, P. Pajic, E. K. Daugherity, X. Chen, S. Schultz-Cherry, H. C. Aguilar, A. Varki, C. R. Parrish

This study examines how modified sialic acids in mucus and erythrocytes affect influenza A virus HA and NA functions, finding that these modifications inhibit viral binding and cleavage.

bioRxiv · Oct 10, 2019 · PreprintMicrobiology

Influenza Viruses in Mice: Deep Sequencing Analysis of Serial Passage and Effects of Sialic Acid Structural Variation

B. R. Wasik, I. E. H. Voorhees, K. N. Barnard, B. K. Lawrence, W. Weichert, G. Hood, A. Nogales, L. Martinez-Sobrido, E. C. Holmes, C. R. Parrish

This study analyzes influenza A virus evolution in mice during serial passage, finding varied mutation patterns and no clear adaptive evolution or sialic acid-related sequence differences.

bioRxiv · Jun 27, 2019Microbiology

Expression of 9-O- and 7,9-O-acetyl modified sialic acids in cells and their effects on influenza viruses

K. N. Barnard, B. R. Wasik, J. R. LaClair, W. Weichert, B. K. Lawrence, C. R. Parrish

The paper examines the expression and effects of 9-O- and 7,9-O-acetyl modified sialic acids on influenza virus infections in human and canine cells.

bioRxiv · May 25, 2019Cell Biology