A physicochemical roadmap of yeast replicative aging
S. N. Mouton, D. Thaller, M. M. Crane, I. L. Rempel, A. Steen, M. Kaeberlein, C. P. Lusk, A. Boersma, L. M. Veenhoff
This study measures physicochemical changes in yeast cells during replicative aging, finding acidification and organellar crowding contribute to homeostatic decline.
bioRxiv · Nov 29, 2019Biophysics