Author

I. Lara-Saez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Enguita· 1 shared A. Mencia· 1 shared C. Scaife· 1 shared D. de Prado-Verdun· 1 shared D. E. MacHugh· 1 shared E. Recuero· 1 shared G. P. McHugo· 1 shared J. S. McKay· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. B. Enguita

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Non-viral CRISPR/Cas9 Mutagenesis for Streamlined Generation of Mouse Lung Cancer Models

I. Lara-Saez, A. Mencia, E. Recuero, Y. Li, M. Garcia, M. Oteo, M. I. Gallego, A. B. Enguita, D. de Prado-Verdun, S. A, W. Wang, R. Garcia-Escudero, R. Murillas, M. Santos

This paper introduces a non-viral CRISPR/Cas9 method using cationic polymers to generate mouse lung cancer models by inactivating tumor suppressor genes, enabling rapid and flexible hypothesis testing.

bioRxiv · Dec 21, 2023 · PreprintCancer Biology

Unveiling the Role of Endoplasmic Reticulum Stress Pathways in Canine Demodicosis

P. Kelly, G. P. McHugo, C. Scaife, S. Peters, M. L. Stevenson, J. S. McKay, D. E. MacHugh, I. Lara-Saez, R. Breathnach

This study identifies endoplasmic reticulum stress pathways as contributors to canine demodicosis through immunosuppressive mechanisms involving M2 macrophages and TLR2 modulation.

bioRxiv · Aug 11, 2023Immunology