BiochemistrybioRxiv
An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function
N. Cuesta, J. M. Contreras, J. Sanchez-Waldermer…·I. Plaza-Menacho
This paper identifies an allosteric switch between c-Src's activation loop and a c-terminal phospho-motif that regulates auto-phosphorylation, enzyme specificity, and non-catalytic function.
DOI 10.1038/s41467-023-41890-7