Author

I. Ortiz-Caraveo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

D. J. Schodt· 2 shared K. A. Lidke· 2 shared A. C. Gibson· 1 shared A. Kiyatkin· 1 shared A. Rajput· 1 shared B. S. Wilson· 1 shared C. Franco Nitta· 1 shared C. Hu· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiophysics

D. J. Schodt

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2 papers

Recent·Most cited

Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes

K. C. Mudumbi, E. A. Burns, D. J. Schodt, Z. O. Petrova, A. Kiyatkin, L. W. Kim, E. M. Mangiacapre, I. Ortiz-Caraveo, H. R. Ortiz, C. Hu, K. D. Ashtekar, K. A. Lidke, D. Lidke, M. A. Lemmon

This study investigates how EGFR dimers and higher-order oligomers form and interact in cell membranes using SPT and FRET, revealing the role of the tyrosine kinase domain in oligomerization.

bioRxiv · Apr 10, 2023Biophysics

EGFR transactivates RON to drive oncogenic crosstalk

C. Franco Nitta, E. W. Green, E. D. Jhamba, J. M. Keth, I. Ortiz-Caraveo, R. M. Grattan, D. J. Schodt, A. C. Gibson, A. Rajput, K. A. Lidke, M. P. Steinkamp, B. S. Wilson, D. S. Lidke

This study identifies EGFR-dependent phosphorylation of RON and shows direct EGFR-RON interactions drive oncogenic crosstalk, contributing to therapeutic resistance.

bioRxiv · Aug 11, 2020 · PreprintCancer Biology