Author

H. R. Ortiz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:proteomics· 2 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. Ramonett· 2 shared M. Karthikeyan· 2 shared N. Y. Lee· 2 shared P. C. Flores· 2 shared P. R. Langlais· 2 shared T. Ahmed· 2 shared A. Kiyatkin· 1 shared C. Hu· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

A. Ramonett

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ER structural remodeling requires TAK1/ATAT1-induced microtubule acetylation

H. R. Ortiz, P. C. Flores, A. Ramonett, T. Ahmed, N. A. Ellis, P. R. Langlais, M. Karthikeyan, N. Y. Lee

The paper shows TAK1 activates TAT1 to acetylate microtubules, promoting ER tubulation and cell survival by downregulating BOK.

bioRxiv · Apr 20, 2023 · PreprintCell Biology

Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes

K. C. Mudumbi, E. A. Burns, D. J. Schodt, Z. O. Petrova, A. Kiyatkin, L. W. Kim, E. M. Mangiacapre, I. Ortiz-Caraveo, H. R. Ortiz, C. Hu, K. D. Ashtekar, K. A. Lidke, D. Lidke, M. A. Lemmon

This study investigates how EGFR dimers and higher-order oligomers form and interact in cell membranes using SPT and FRET, revealing the role of the tyrosine kinase domain in oligomerization.

bioRxiv · Apr 10, 2023Biophysics

Identification of Mfn2-S249 as a Phosphoregulatory Switch of Mitochondrial Fusion Dynamics

S. Kumar, A. Ramonett, T. Ahmed, E. Kwak, P. C. Flores, H. R. Ortiz, P. R. Langlais, M. Karthikeyan, N. Y. Lee

The paper identifies Mfn2-S249 as a phosphoregulatory switch controlling mitochondrial fusion dynamics through TAK1-mediated phosphorylation, affecting mitochondrial morphology and energy homeostasis.

bioRxiv · Jan 11, 2022 · PreprintCell Biology