Author

I. Pineda-Torra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:metabolomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

G. A. Robinson· 2 shared A. Radziszewska· 1 shared B. Rubio Cuesta· 1 shared C. Ciurtin· 1 shared D. A. Isenberg· 1 shared D. Owen· 1 shared E. Chrifi-Alaoui· 1 shared E. E. Jury· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

G. A. Robinson

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Author profile →

3 papers

Recent·Most cited

LXR alters CD4+ T cell function through direct regulation of glycosphingolipid synthesis

K. E. Waddington, G. A. Robinson, B. Rubio Cuesta, E. Chrifi-Alaoui, S. Andreone, K. S. Poon, I. Ivanova, L. Martin-Gutierrez, D. Owen, E. E. Jury, I. Pineda-Torra

This study shows LXR regulates glycosphingolipid synthesis in CD4+ T cells, altering lipid balance and reducing plasma membrane order, which dampens pro-inflammatory T cell function.

bioRxiv · Sep 2, 2020 · PreprintImmunology

Sex differences in autoimmunity could be associated with altered regulatory T cell phenotype and lipoprotein metabolism

G. A. Robinson, K. Waddington, M. Adriani, A. Radziszewska, H. Peckham, D. A. Isenberg, Y. Ioannou, C. Ciurtin, I. Pineda-Torra, E. Jury

The paper examines sex differences in regulatory T cell phenotype and lipoprotein metabolism in healthy adolescents and those with juvenile SLE, finding gender-specific Treg function and metabolomic profiles that are altered in JSLE.

bioRxiv · Sep 8, 2019 · PreprintImmunology

Aged insulin resistant macrophages reveal dysregulated cholesterol biosynthesis, a pro-inflammatory profile and reduced foam cell formation capacity

G. Chabrier, S. Hobson, N. Yuldasheva, M. T. Kearney, S. Schurmans, I. Pineda-Torra, M. C. Gage

This study investigates how insulin resistance in aged macrophages affects inflammation, cholesterol biosynthesis, and foam cell formation, finding pro-inflammatory changes and reduced foam cell capacity.

bioRxiv · Nov 9, 2018 · PreprintImmunology