The PqsE active site as a target for small molecule antimicrobial agents against Pseudomonas aeruginosa
I. R. Taylor, P. D. Jeffrey, D. A. Moustafa, J. B. Goldberg, B. L. Bassler
This paper shows that disrupting the PqsE-RhlR interaction reduces P. aeruginosa infection in mice and presents new molecules targeting the PqsE active site.
bioRxiv · Apr 21, 2022Microbiology