I. Silva

A Plasmodium falciparum MORC protein complex modulates epigenetic control of gene expression through interaction with heterochromatin.

This study identifies PfMORC as a chromatin-associated protein in Plasmodium falciparum that modulates gene expression through interactions with chromatin remodelers and transcription factors.

movedesign: Shiny R app to evaluate sampling design for animal tracking movement studies

movedesign evaluates sampling design for animal tracking studies to assess precision in estimating home range, speed, and distance traveled.

Clarifying space use concepts in ecology: range vs. occurrence distributions

This paper distinguishes between range and occurrence distributions in ecology, showing that conflating them can lead to incorrect ecological inferences and conservation practices.

Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscape

The paper examines SHM patterns in immunoglobulin variable regions and finds they are not significantly correlated with local transcriptional features.

Simultaneous isolation of proximal and distal lung progenitor cells from individual mice using a 3D printed guide reduces proximal cell contamination of distal lung epithelial cell isolations

This paper introduces a 3D-printed guide to isolate proximal and distal lung progenitor cells from mice, reducing contamination and improving the accuracy of in vitro assays.

How do King Cobras move across a major highway? Unintentional wildlife crossing structures may facilitate movement.

This study investigates how King Cobras cross a major highway in Thailand and finds that unintentional crossing structures may help them safely traverse roads.

Direct tissue sensing reprograms TLR4+ Tfh-like cells inflammatory profile in the joints of rheumatoid arthritis patients

The paper identifies TLR4+ Tfh-like cells in RA patients that switch from producing IL-21 to IL-17 upon joint exposure, contributing to tissue damage.

Lots of movement, little progress: A review of reptile home range literature

This paper reviews reptile home range studies from 2000-2019, highlighting methodological biases and gaps in data reporting, and recommends improved analytical techniques and open data practices.

No room to roam: King Cobras reduce movement in agriculture

This study examines how King Cobras adjust their movement patterns in response to agricultural landscapes, finding reduced movement in agricultural areas compared to forested regions.

Revisiting reptile home ranges: moving beyond traditional estimators with dynamic Brownian Bridge Movement Models

This study evaluates home range estimation methods for reptiles, finding that dynamic Brownian Bridge Movement Models outperform traditional methods across various tracking regimes.

APOBEC-mediated DNA alterations: a possible new mechanism of carcinogenesis in EBV-positive gastric cancer

The paper identifies a positive correlation between APOBEC3 mRNA-expression and APOBEC-mutation signature in EBV+ gastric cancer, suggesting APOBEC3 upregulation may increase mutation load.