Author

I. Szabo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. Balint· 1 shared A. Gyenesei· 1 shared A. Mattarei· 1 shared A. Nagy· 1 shared B. Somogyi· 1 shared C. I. Pereszlenyi· 1 shared C. Paradisi· 1 shared D. Rioux· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Balint

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Long-term population decline of a genetically homogenous continental-wide top Arctic predator

M. Gousy-Leblanc, J.-F. Therrien, T. Broquet, D. Rioux, N. Curt-Grand-Gaudin, N. Tissot, S. Tissot, I. Szabo, L. Wilson, J. T. Evans, V. Bowes, G. Gauthier, K. L. Wiebe, G. Yannic, N. Lecomte

This study uses genetic analysis to show that Snowy Owls across North America form a genetically homogenous population with no differentiation, despite long-distance dispersal, and reveals a long-term population decline linked to climate change.

bioRxiv · Apr 29, 2022Ecology

Voltage-Gated Potassium Channel Kv1.3 as a Therapeutic Target for Pancreatic Ductal Adenocarcinoma

W. Li, G. Wilson, M. Bachmann, J. Wang, A. Mattarei, C. Paradisi, M. Edwards, I. Szabo, E. Gulbins, S. Ahmad, S. Patel

This study shows Kv1.3 is highly expressed in human PDAC and novel Kv1.3 inhibitors combined with chemotherapy significantly reduce tumor growth in mouse models.

bioRxiv · Feb 3, 2021 · PreprintCancer Biology

Molecular simulations unravel the molecular principles that mediate selective permeability of carboxysome shell protein

M. Faulkner, I. Szabo, S. L. Weetman, F. Sicard, R. G. Huber, P. J. Bond, E. Rosta, L.-N. Liu

This study uses molecular simulations to uncover how carboxysome shell protein CcmK2 controls molecular permeability through its central pore, validated by experimental mutagenesis.

Scientific Reports · Oct 15, 2020Peer-reviewedBiophysics

Multiple SARS-CoV-2 introductions shaped the early outbreak in Central Eastern Europe: comparing Hungarian data to a worldwide sequence data-matrix

G. Kemenesi, S. Zeghbib, B. Somogyi, G. E. Toth, K. Banyai, N. Solymosi, P. M. Szabo, I. Szabo, A. Balint, P. Urban, R. Herczeg, A. Gyenesei, A. Nagy, C. I. Pereszlenyi, G. Babinszky, , F. Jakab

The paper analyzes SARS-CoV-2 genomic data from Hungary to identify multiple introduction events into Central-Eastern Europe using haplotype networks and phylogenetic analysis.

bioRxiv · May 6, 2020Microbiology