Author

L.-N. Liu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biophysics· 3 Biochemistry· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 6 Research Focus:cell type annotation· 6 Approach:experimental assay· 6 Assay:cryo-EM· 4 Research Focus:cell signaling & trafficking· 3 Approach:microscopy & imaging analysis· 3 Research Focus:protein folding & dynamics· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

G. Dykes· 3 shared P. Zhang· 3 shared T. Ni· 3 shared Y. Sun· 3 shared F. Huang· 2 shared Y. Zhu· 2 shared A. Beavil· 1 shared A. Yamagata· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiophysics

G. Dykes

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Intrinsically disordered CsoS2 acts as a general molecular thread for α-carboxysome shell assembly

T. Ni, Q. Jiang, P. C. Ng, J. Shen, H. Dou, Y. Zhu, J. Radecke, G. F. Dykes, F. Huang, L.-N. Liu, P. Zhang

The paper investigates the role of intrinsically disordered CsoS2 in α-carboxysome shell assembly using synthetic engineering and cryoEM structures, revealing its function as a molecular thread and identifying a conserved interaction motif.

bioRxiv · Jun 24, 2023Microbiology

Tales of Two α-Carboxysomes: the Structure and Assembly of Cargo Rubisco

T. Ni, Y. Sun, W. Seaton-Burn, M. M. Al-Hazeem, Y. Zhu, X. Yu, L.-N. Liu, p. zhang

This study uses cryo-electron tomography to reveal the 3D organization of Rubisco in two types of carboxysomes from different bacteria, showing distinct structural arrangements and responses to calcium treatment.

bioRxiv · Mar 15, 2022 · PreprintMicrobiology

Single-particle cryo-EM analysis of the shell architecture and internal organization of an intact α-carboxysome

S. L. Evans, M. Al-Hazeem, D. Mann, N. Smetacek, A. Beavil, Y. Sun, T. Chen, G. Dykes, L.-N. Liu, J. Bergeron

This study uses single-particle cryo-EM to determine the structure of a native α-carboxysome from a marine cyanobacterium, revealing its shell architecture and internal enzyme organization.

bioRxiv · Feb 18, 2022Biophysics

Structural basis for the assembly and electron transport mechanisms of the dimeric photosynthetic RC-LH1 supercomplex

P. Cao, L. Bracun, A. Yamagata, B. Christianson, T. Negami, B. Zou, T. Terada, D. P. Canniffe, M. Shirouzu, M. Li, L.-N. Liu

The paper reports cryo-EM structures of the dimeric RC-LH1 supercomplex from Rhodobacter sphaeroides, revealing the architecture, assembly mechanism, and electron transport pathways involving PufX and PufY.

bioRxiv · Dec 17, 2021 · PreprintBiochemistry

Biogenesis of a bacterial metabolosome for propanediol utilization

M. Yang, N. Wenner, G. Dykes, Y. Li, X. Zhu, Y. Sun, F. Huang, J. C. D. Hinton, L.-N. Liu

This study investigates the biogenesis of propanediol-utilization metabolosomes in bacteria, revealing both 'Shell first' and 'Cargo first' assembly pathways.

bioRxiv · Dec 9, 2021Microbiology

Probing the biogenesis pathway and dynamics of thylakoid membranes

T. Huokko, T. Ni, G. Dykes, D. Simpson, P. Brownridge, F. Conradi, R. Beynon, P. Nixon, C. Mullineaux, P. Zhang, L.-N. Liu

The paper investigates thylakoid membrane biogenesis in cyanobacteria by modulating light intensity, revealing the spatial-temporal dynamics of protein complex insertion and membrane organization.

bioRxiv · May 5, 2021Plant Biology

Identification of a new orthonairovirus associated with human febrile illness in China

J. Ma, X.-L. Lv, X. Zhang, S.-Z. Han, Z.-D. Wang, L. Li, H.-T. Sun, L.-X. Ma, Z.-L. Cheng, J.-W. S. Shao, C. Chen, Y.-H. Zhao, L. Sui, L.-N. Liu, J. Qian, , Q. Liu

This study identifies a new orthonairovirus, SGLV, associated with human febrile illness in northeastern China, showing its presence in ticks and clinical symptoms in infected patients.

bioRxiv · Oct 24, 2020Microbiology

Molecular simulations unravel the molecular principles that mediate selective permeability of carboxysome shell protein

M. Faulkner, I. Szabo, S. L. Weetman, F. Sicard, R. G. Huber, P. J. Bond, E. Rosta, L.-N. Liu

This study uses molecular simulations to uncover how carboxysome shell protein CcmK2 controls molecular permeability through its central pore, validated by experimental mutagenesis.

Scientific Reports · Oct 15, 2020Peer-reviewedBiophysics

Structural visualization of septum formation in Staphylococcus warneri using atomic force microscopy

H.-N. Su, K. Li, X.-X. Yuan, M.-Y. Zhang, S.-M. Liu, X.-L. Chen, L.-N. Liu, Y.-Z. Zhang

This study uses microscopy techniques to reveal the structural features of the septum in Staphylococcus warneri, showing it is composed of two layers with concentric peptidoglycan rings.

bioRxiv · May 24, 2020Biophysics