Author

I. Tietjen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Organism:plant (other)· 1 Organism:rat· 1

Frequent Co-Authors

A. J. Cutts· 1 shared A. K. Camara· 1 shared A. M. Balde· 1 shared A. Soumah· 1 shared C. J. Cohen· 1 shared C. Young· 1 shared E. S. Balde· 1 shared E. T. Register· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

A. J. Cutts

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Traditional uses and pharmacological activities of Tetracera alnifolia (Wild) Drake

A. K. Camara, E. S. Balde, M. S. T. Diallo, M. K. Camara, T. V. Bah, M. Conde, A. Soumah, I. Tietjen, A. M. Balde

This study investigates the traditional use and pharmacological activities of Tetracera alnifolia, finding antimicrobial and antiviral properties in its extracts.

bioRxiv · Feb 7, 2024 · PreprintPharmacology & Toxicology

Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1 (DMT1): Preclinical Efficacy Against Iron Overload and Safety Evaluation

A. J. Cutts, S. Chowdhury, L. Ratkay, M. Eyers, C. Young, R. Namdari, J. Cadieux, N. Chahal, M. Grimwood, Z. Zhang, S. Lin, I. Tietjen, Z. Xie, L. Robinette, L. Sojo, , C. J. Cohen

This paper identifies XEN602, a potent, gut-restricted DMT1 inhibitor, showing efficacy in reducing iron overload in rats and pigs with minimal systemic exposure.

bioRxiv · Sep 1, 2022Pharmacology & Toxicology

The natural stilbenoid (-)-hopeaphenol inhibits cellular entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7 and B.1.351 variants

I. Tietjen, J. Cassel, E. T. Register, X. Y. Zhou, T. E. Messick, F. Keeney, L. D. Lu, K. D. Beattie, T. Rali, H. C. Ertl, J. M. Salvino, R. A. Davis, L. J. Montaner

This paper identifies (-)-hopeaphenol and related stilbenoids as potent inhibitors of SARS-CoV-2 entry across multiple variants by blocking spike protein-ACE2 interaction.

bioRxiv · Apr 29, 2021Microbiology