Author

I. Y. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1

Frequent Co-Authors

A. deCarvalho· 1 shared A. M. Robin· 1 shared A. Makherjee· 1 shared A. V. Castro· 1 shared B. S. Katzenellenbogen· 1 shared C. A. Natale· 1 shared D. Chitale· 1 shared H. Noushmehr· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. deCarvalho

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2 papers

Recent·Most cited

CHRM1 is a Druggable Melanoma Target Whose Endogenous Activity is Determined by Inherited Genetic Variation in DOPA Production

M. Doepner, C. A. Natale, I. Y. Lee, S. Venkat, S. H. Kim, J. A. Katzenellenbogen, B. S. Katzenellenbogen, M. Feigin, T. W. Ridky

This study identifies CHRM1 as a druggable melanoma target influenced by genetic variation in DOPA production, showing DOPA inhibits CHRM1 to suppress melanoma proliferation.

bioRxiv · Mar 3, 2021 · PreprintCancer Biology

Detection of glioma and prognostic subtypes by non-invasive circulating cell-free DNA methylation markers

H. Noushmehr, T. S. Sabedot, T. M. Malta, K. Nelson, J. Snyder, M. Wells, A. deCarvalho, A. Makherjee, D. Chitale, M. Mosella, K. Asmaro, A. M. Robin, M. L. Rosenblum, T. Mikkelsen, J. Rock, , A. V. Castro

This study identifies non-invasive circulating DNA methylation markers that can detect glioma and predict its prognosis from serum samples.

bioRxiv · Apr 8, 2019 · PreprintCancer Biology