Author

J. Snyder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Animal Behavior & Cognition· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Assay:DNA methylation· 3 Organism:mouse· 3 Approach:statistical model· 2

Frequent Co-Authors

H. Noushmehr· 3 shared T. M. Malta· 3 shared T. S. Sabedot· 3 shared A. V. Castro· 2 shared J. Rock· 2 shared L. M. Poisson· 2 shared M. Wells· 2 shared S. Kalkanis· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

H. Noushmehr

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A Pumpless, High-Throughput Microphysiological SystemConfirms Enteric Innervation of Duodenal Epithelium Strengthensthe Barrier Function

K. Nichols, J. Snyder, R. Koppes, A. Koppes

This paper introduces a high-throughput microphysiological system that demonstrates enteric innervation enhances duodenal epithelial barrier function and reduces EGF expression.

bioRxiv · Jun 3, 2023 · PreprintBioengineering

Leptomeningeal anti-tumor immunity follows unique signaling principles

J. Remsik, X. Tong, R. Z. Kunes, M. J. Li, A. Osman, K. Chabot, U. Sener, J. A. Wilcox, D. Isakov, J. Snyder, T. Bale, R. Chaligne, D. D. Pe'er, A. Boire

The paper investigates IFN-γ signaling in leptomeningeal metastasis and shows its role in recruiting myeloid cells to control tumor growth.

bioRxiv · Mar 17, 2023 · PreprintCancer Biology

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and represents a therapeutic target in myelofibrosis

A. Dunbar, D. Kim, M. Lu, M. Farina, J. L. Yang, Y. Park, F. Gobbo, P. Verachi, F. Martelli, A. Karzai, W. Xiao, L. Xia, N. Elmansy, M. Kleppe, Z. Chen, , R. Hoffman

This study identifies CXCL8/CXCR2 signaling as a driver of bone marrow fibrosis in myelofibrosis and shows its therapeutic potential through genetic and pharmacologic inhibition.

bioRxiv · Dec 8, 2021Cancer Biology

DNA Methylation-based Signatures Classify Sporadic Pituitary Tumors According to Clinicopathological Features.

M. S. Mosella, T. S. Sabedot, T. C. Silva, T. M. Malta, F. D. Segato, K. P. Asmaro, M. Wells, A. Mukherjee, L. M. Poisson, J. Snyder, A. C. deCarvalho, T. Walbert, T. Aho, S. Kalkanis, P. C. Elias, , A. V. Castro

This paper identifies and validates DNA methylation signatures that classify sporadic pituitary tumors based on clinicopathological features and adenohypophyseal cell lineages.

Neuro-Oncology · Feb 25, 2021Peer-reviewedCancer Biology

Pathfinder: open source software for analyzing spatial navigation search strategies

M. B. Cooke, T. P. O'Leary, P. Harris, R. E. Brown, J. Snyder

Pathfinder is an open-source tool for analyzing spatial navigation strategies, demonstrating its ability to characterize search strategies in mice learning a water maze.

bioRxiv · Jul 26, 2019Animal Behavior & Cognition

Detection of glioma and prognostic subtypes by non-invasive circulating cell-free DNA methylation markers

H. Noushmehr, T. S. Sabedot, T. M. Malta, K. Nelson, J. Snyder, M. Wells, A. deCarvalho, A. Makherjee, D. Chitale, M. Mosella, K. Asmaro, A. M. Robin, M. L. Rosenblum, T. Mikkelsen, J. Rock, , A. V. Castro

This study identifies non-invasive circulating DNA methylation markers that can detect glioma and predict its prognosis from serum samples.

bioRxiv · Apr 8, 2019 · PreprintCancer Biology

Glioma CpG Island Methylator Phenotype (G-CIMP): Biological and Clinical Implications

T. M. Malta, C. F. Souza, T. S. Sabedot, T. C. Silva, M. Q. S. Mosella, S. N. Kalkanis, J. Snyder, A. V. B. Castro, H. Noushmehr

This paper reviews the biological and clinical implications of G-CIMP subsets in gliomas, highlighting their role in prognosis and potential for personalized therapy.

bioRxiv · Sep 14, 2017Cancer Biology