Genetic variation influences pluripotent ground state stability in mouse embryonic stem cells through a hierarchy of molecular phenotypes
Daniel A. Skelly, Anne Czechanski, Candice Byers, Selcan C. Aydin, Catrina A. Spruce, Chris Olivier, Kwangbom Choi, Daniel M. Gatti, Narayanan Raghupathy, Alexander R. Stanton, Matthew J. Vincent, Stephanie Dion, Ian Greenstein, Matthew T Pankratz, Devin K. Porter, , Laura G. Reinholdt
The paper identifies genetic variants influencing metastability in mouse embryonic stem cells by analyzing gene expression and chromatin accessibility in 185 genetically diverse cells.
bioRxiv · Feb 17, 2019 · PreprintGenomics