Author

Idris A. Barakat

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

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Amanda L. WaterburyiD· 1 shared Andrea MatteviiD· 1 shared Brian B. LiauiD· 1 shared Ceejay LeeiD· 1 shared Eunju NamiD· 1 shared Haibin MaoiD· 1 shared Hanjie JiangiD· 1 shared Hui Si KwokiD· 1 shared

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Amanda L. WaterburyORCID

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1 paper

Recent·Most cited

Molecular BiologyNaturePeer-reviewedFeb 12, 2025

Asymmetric Engagement of Dimeric CRL3KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes

Megan J. R. Yeo, Olivia Zhang, Xiaowen Xie…·Ning Zheng

This paper identifies UM171 as a molecular glue that promotes degradation of HDAC1/2 complexes by inducing asymmetric interactions between KBTBD4 and HDAC1.

59 citationstop 1%

humanproteomics

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