Author

Fabian Bachinger

Berlin Institute of Health at Charité - Universitätsmedizin BerlinORCID 0009-0003-9889-3811Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1

Frequent Co-Authors

Ludovic VallieriD· 2 shared Alec S.T. SmithiD· 1 shared Alessandro BerteroiD· 1 shared Annabelle WurmseriD· 1 shared Brandon Tyler WesleyiD· 1 shared Carola Maria MorelliD· 1 shared Charis‐Patricia Segeritz· 1 shared Daniel Ortmann· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersSynthetic Biology

Ludovic VallierORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintOct 27, 2026

Genetic control couples TGFβ-independent pluripotent stem cell renewal to deterministic forward programming across germ layers

Sveva Bottini, Francesca Amodeo, Divyashree Avnoor…·Alessandro Bertero

This paper introduces GERALT, a genetic circuit that enables TGFβ-independent hiPSC renewal and inducible lineage programming, improving differentiation efficiency and reducing medium complexity.

DOI 10.64898/2026.10.25.761636

humanbulk RNA-seq

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Developmental BiologyeLifePeer-reviewedJul 26, 2022

Generation of functional hepatocytes by forward programming with nuclear receptors

Rute A. Tomaz, Ekaterini D. Zacharis, Fabian Bachinger…·Ludovic Vallier

This study generates functional hepatocytes from human pluripotent stem cells using forward programming with nuclear receptors, bypassing the limitations of traditional differentiation methods.

32 citations

humanexperimental assay

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