Mariya Chhatriwala

This study shows NGN3 protein oscillations control timing of human pancreatic endocrine differentiation, not fate, through fold-change detection via an incoherent feedforward motif.

This study generates functional hepatocytes from human pluripotent stem cells using forward programming with nuclear receptors, bypassing the limitations of traditional differentiation methods.

The paper uses single-cell RNA-seq of differentiating iPS cells from 125 donors to identify expression quantitative trait loci influencing gene expression during endoderm differentiation.

The paper uses single-cell profiling of expression and DNA methylation to study splicing regulation and heterogeneity in human induced pluripotent stem cells.