PKA prevents resection of DNA double strand breaks and favor non-homologous end-joining
Houaria Khater-Sellou, Indiana Magdalou, Vasily V. Ogryzko, Bernard S. López
This study shows PKA promotes NHEJ over resection in DSB repair by interacting with 53BP1, highlighting PKA's role in DNA damage response and genome stability.
bioRxiv · Aug 29, 2024 · PreprintMolecular Biology