A time-resolved atlas of histone modifications during mitotic entry
Natalia Y. Kochanova, Moonmoon Deb, Marco Borsò, Shaun Webb, Ipek Ustun, Kumiko Samejima, Ignasi Forné, Itaru Samejima, Caitlin Reid, Linfeng Xie, James R. Paulson, Axel Imhof, William C. Earnshaw
The paper uses mass spectrometry to analyze histone modifications during mitotic entry, identifying three phosphorylation programs and showing H3 T3 phosphorylation marks heterochromatin, not just centromeres.
Molecular Cell · Apr 23, 2026Peer-reviewedCell Biology