Cancer BiologyAdvanced SciencePeer-reviewed
Endocytic control of cell-autonomous and non-cell-autonomous functions of p53
Roberta Cacciatore, Andrea Basile, Stefano Freddi…·Pier Paolo Di Fiore
This study shows that NUMB's Ex3 exon directs it to the plasma membrane, forming a complex with SNX9 that recruits and transports p53 via exosomes, enabling p53-dependent transcriptional activity in recipient cells.
DOI 10.1002/advs.202513765