Author

Giuseppe Ciossani

European Institute of OncologyORCID 0000-0001-5293-4292Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Giuseppe Ciossani1 paper

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alessandro CuomoiD· 2 shared Irene Schiano Lomoriello· 2 shared Ivan Nicola ColalucaiD· 2 shared Luigi SciettiiD· 2 shared Pier Paolo Di FioreiD· 2 shared Roberta Cacciatore· 2 shared Salvatore PeceiD· 2 shared Sara SigismundiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Alessandro CuomoORCID

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2 papers

Recent·Most cited

Endocytic control of cell-autonomous and non-cell-autonomous functions of p53

Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, , Pier Paolo Di Fiore

This study shows that NUMB's Ex3 exon directs it to the plasma membrane, forming a complex with SNX9 that recruits and transports p53 via exosomes, enabling p53-dependent transcriptional activity in recipient cells.

Advanced Science · Jan 30, 2026Peer-reviewedCancer Biology

Targeting GL-Lect driven endocytosis to suppress cell plasticity in breast cancer

Amir Fardin, Andrea Francesco Benvenuto, Irene Schiano Lomoriello, Chiara Tordonato, Micaela Quarto, Stefano Freddi, Giovanni Giangreco, Giovanni Bertalot, Francesca Montani, Ivan Nicola Colaluca, Roberta Cacciatore, Andrea Raimondi, Maria Giovanna Jodice, Maria Grazia Malabarba, Luigi Scietti, , Sara Sigismund

This study identifies GL-Lect driven endocytosis as a driver of metastatic plasticity in breast cancer and shows pharmacologic inhibition can suppress invasive phenotypes.

bioRxiv · Jan 8, 2026 · PreprintCancer Biology