Author

Isaac Hernan Esparza Borquez

BioNTech (Germany)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander MuikiD· 1 shared Aniello FedericoiD· 1 shared Ayline KübleriD· 1 shared Eliana StanganelloiD· 1 shared Elif DikeniD· 1 shared Ferdia BatesiD· 1 shared Friederike GiesekeiD· 1 shared Fulvia VascottoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alexander MuikORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintMay 11, 2026

Lung-targeted cytokine-coding RNA-lipoplexes induce T and NK cell-mediated anti-tumor immune response

Ayline Kübler, Sophie-Christin Linkenbach, Fulvia Vascotto…·Uğur Şahin

This study shows that lung-targeted cytokine RNA-lipoplexes enhance anti-tumor immunity by activating T and NK cells and reducing Tregs, with efficacy in murine models and human lung tumor cultures.

DOI 10.64898/2026.05.06.723126

mousebulk RNA-seq

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