Author

Elif Diken

Johannes Gutenberg University MainzORCID 0000-0002-5300-7172Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Ayline KübleriD· 2 shared Eliana StanganelloiD· 2 shared Mustafa DikeniD· 2 shared Özlem Akilli‐ÖztürkiD· 2 shared Uğur ŞahiniD· 2 shared Ahmad Al AlwashiD· 1 shared Alessandra GarganoiD· 1 shared Alexander MuikiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 3, 2026

Mapping the immune landscape in small cell lung cancer unveils a distinct tumor-reactive CD8+ T cell molecular signature

Krutika Khinvasara, Elif Diken, Jennifer V. Gerbracht…·LAURA D. KOLB

This study identifies a CD8+ T cell molecular signature specific to small cell lung cancer, showing its prognostic value and potential for immunotherapy.

DOI 10.64898/2026.06.29.735200

humanscRNA-seq

ImmunologybioRxivPreprintMay 11, 2026

Lung-targeted cytokine-coding RNA-lipoplexes induce T and NK cell-mediated anti-tumor immune response

Ayline Kübler, Sophie-Christin Linkenbach, Fulvia Vascotto…·Uğur Şahin

This study shows that lung-targeted cytokine RNA-lipoplexes enhance anti-tumor immunity by activating T and NK cells and reducing Tregs, with efficacy in murine models and human lung tumor cultures.

DOI 10.64898/2026.05.06.723126

mousebulk RNA-seq