ImmunologybioRxivPreprint
Lung-targeted cytokine-coding RNA-lipoplexes induce T and NK cell-mediated anti-tumor immune response
Ayline Kübler, Sophie-Christin Linkenbach, Fulvia Vascotto…·Uğur Şahin
This study shows that lung-targeted cytokine RNA-lipoplexes enhance anti-tumor immunity by activating T and NK cells and reducing Tregs, with efficacy in murine models and human lung tumor cultures.
DOI 10.64898/2026.05.06.723126