Author

Isabel Bjork

University of California, Santa Cruz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:variant calling· 1

Frequent Co-Authors

David H. HaussleriD· 3 shared Olena M. VaskeiD· 3 shared A. Geoffrey LyleiD· 2 shared Drew ThompsoniD· 2 shared Ellen Towle KephartiD· 2 shared Holly C. BealeiD· 2 shared Katrina LearnediD· 2 shared Lauren SandersiD· 2 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

David H. HausslerORCID

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3 papers

Recent·Most cited

Comparative analysis of RNA expression in a single institution cohort of pediatric cancer patients

Yvonne A. Vasquez, Holly C. Beale, Lauren Sanders, A. Geoffrey Lyle, Ellen Towle Kephart, Katrina Learned, Drew Thompson, Jennifer Peralez, Amy Li, Min Huang, Kimberly A. Pyke‐Grimm, Sofie R. Salama, David H. Haussler, Isabel Bjork, L. Spunt Sheri, Olena M. Vaske

The paper evaluates the CARE pipeline for identifying druggable targets in pediatric cancers using RNA-Seq data from 33 patients, showing 94% of cases had clinically significant findings.

npj Precision Oncology · Mar 21, 2025Peer-reviewedGenetic & Genomic Medicine

A new SARS-CoV-2 lineage that shares mutations with known Variants of Concern is rejected by automated sequence repository quality control

Bryan P. Thornlow, Angie S. Hinrichs, Miten Jain, Namrita Dhillon, Scott La, Joshua D. Kapp, Ikenna Anigbogu, Molly Cassatt‐Johnstone, Jakob McBroome, Maximilian Haeussler, Yatish Turakhia, Terren R. Chang, Hugh E. Olsen, Jeremy R. Sanford, Michael D. Stone, , Russell B Corbett-Detig

The paper reports a SARS-CoV-2 lineage with mutations from known variants of concern that is rejected by sequence repositories due to a deletion, suggesting underestimation of its frequency.

bioRxiv · Apr 5, 2021 · PreprintGenomics

The case for using Mapped Exonic Non-Duplicate (MEND) read counts in RNA-Seq experiments: examples from pediatric cancer datasets

Holly C. Beale, Jacquelyn M. Roger, Matthew A. Cattle, Liam T. McKay, Drew Thompson, Katrina Learned, A. Geoffrey Lyle, Ellen Towle Kephart, Rob Currie, Du Linh Lam, Lauren Sanders, Jacob Pfeil, John Vivian, Isabel Bjork, Sofie R. Salama, , Olena M. Vaske

The paper evaluates the informativeness of reads in bulk RNA-Seq datasets and recommends using MEND reads for accurate gene expression quantification in pediatric cancer studies.

GigaScience · Mar 1, 2021Peer-reviewedGenomics