GDF15 regulates necroptotic cell death through direct interaction with RIPK3
Anastasia Piskopou, Isabella Vinson, Kong Sit, Els Sweep, Maarten A. F. Altelaar, Kelly E. Stecker
The paper identifies GDF15 as a negative regulator of necroptotic cell death by directly interacting with RIPK3, enhancing necroptosis in tumor cells.
bioRxiv · Oct 23, 2025 · PreprintCell Biology