Author

Anastasia Piskopou

Utrecht UniversityORCID 0000-0002-5841-5079Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Kelly E. SteckeriD· 2 shared Maarten A. F. AltelaariD· 2 shared Daniel S. PeeperiD· 1 shared David W. VredevoogdiD· 1 shared Els SweepiD· 1 shared Isabella Vinson· 1 shared Kong Sit· 1 shared Xiangjun KongiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

Kelly E. SteckerORCID

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2 papers

Recent·Most cited

GDF15 regulates necroptotic cell death through direct interaction with RIPK3

Anastasia Piskopou, Isabella Vinson, Kong Sit, Els Sweep, Maarten A. F. Altelaar, Kelly E. Stecker

The paper identifies GDF15 as a negative regulator of necroptotic cell death by directly interacting with RIPK3, enhancing necroptosis in tumor cells.

bioRxiv · Oct 23, 2025 · PreprintCell Biology

Inhibition of TBK1/IKKe mediated RIPK1 phosphorylation sensitizes tumors to immune cell killing

Anastasia Piskopou, David W. Vredevoogd, Xiangjun Kong, Daniel S. Peeper, Maarten A. F. Altelaar, Kelly E. Stecker

This study shows that inhibiting TBK1/IKKe-mediated RIPK1 phosphorylation increases tumor sensitivity to immune cell killing by disrupting TNF signaling.

bioRxiv · May 20, 2025 · PreprintCell Biology