Author

J. A. Gallaher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

A. R. A. Anderson· 2 shared A. C. Hawkins-Daarud· 1 shared C. J. Whelan· 1 shared J. Juliano· 1 shared J. S. Brown· 1 shared K. A. Luddy· 1 shared K. R. Swanson· 1 shared L. Gonzalez-Cuyar· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. R. A. Anderson

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3 papers

Recent·Most cited

Cycling hypoxia selects for constitutive HIF stabilization

M. Pressley, J. A. Gallaher, J. S. Brown, M. R. Tomaszewski, P. Borad, M. Damaghi, R. J. Gillies, C. J. Whelan

The paper develops a mathematical model showing that rapid oxygen fluctuations favor pseudohypoxia by selecting for constitutive HIF stabilization despite reduced cell fitness.

bioRxiv · Oct 28, 2020Cancer Biology

From cells to tissue: How cell scale heterogeneity impacts glioblastoma growth and treatment response

J. A. Gallaher, S. C. Massey, A. C. Hawkins-Daarud, S. S. Noticewala, R. C. Rockne, S. K. Johnston, L. Gonzalez-Cuyar, J. Juliano, O. Gil, K. R. Swanson, P. Canoll, A. R. A. Anderson

This paper develops a hybrid agent-based model to study how intratumor heterogeneity affects glioblastoma growth and treatment response using multiscale data and mathematical frameworks.

bioRxiv · May 26, 2019Cancer Biology

Spatial heterogeneity and evolutionary dynamics modulate time to recurrence in continuous and adaptive cancer therapies

J. A. Gallaher, P. M. Enriquez-Navas, K. A. Luddy, R. A. Gatenby, A. R. A. Anderson

This study models how spatial heterogeneity and evolutionary dynamics affect cancer recurrence under different treatment schedules.

bioRxiv · Sep 8, 2017Cancer Biology