Author

M. R. Tomaszewski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:imaging· 2 Organism:mouse· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

R. J. Gillies· 3 shared A. Ortiz· 1 shared B. V. Jardim Perassi· 1 shared C. J. Whelan· 1 shared D. R. Reed· 1 shared G. V. Martinez· 1 shared H. Enderling· 1 shared J. A. Gallaher· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

R. J. Gillies

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Author profile →

3 papers

Recent·Most cited

Cycling hypoxia selects for constitutive HIF stabilization

M. Pressley, J. A. Gallaher, J. S. Brown, M. R. Tomaszewski, P. Borad, M. Damaghi, R. J. Gillies, C. J. Whelan

The paper develops a mathematical model showing that rapid oxygen fluctuations favor pseudohypoxia by selecting for constitutive HIF stabilization despite reduced cell fitness.

bioRxiv · Oct 28, 2020Cancer Biology

Targeting hypoxic habitats with hypoxia pro-drug evofosfamide in preclinical models of sarcoma

B. V. Jardim Perassi, W. Mu, S. Huang, M. R. Tomaszewski, J. Poleszczuk, M. A. Abdalah, M. M. Budzevich, W. Dominguez-Viqueira, D. R. Reed, M. M. Bui, J. O. Johnson, G. V. Martinez, R. J. Gillies

This paper develops deep-learning models to identify hypoxic tumor regions using MRI and histology, showing their effectiveness in predicting hypoxia and guiding TH-302 therapy response in sarcoma models.

bioRxiv · Oct 6, 2020 · PreprintCancer Biology

T2 heterogeneity provides a sensitive measure of early tumor response to radiotherapy

M. R. Tomaszewski, W. Dominguez Viqueira, A. Ortiz, Y. Shi, J. R. Costello, H. Enderling, S. A. Rosenberg, R. J. Gillies

This paper introduces a T2 MRI-based biomarker to assess early tumor response to radiotherapy in pancreatic cancer models, showing high sensitivity and robustness.

bioRxiv · Apr 21, 2020 · PreprintBiophysics