Author

J. A. M. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Amparo· 1 shared A. A. Dondua· 1 shared A. C. Garcia· 1 shared A. Gill· 1 shared A. J. Aguirre· 1 shared A. Kosztolanyi· 1 shared A. M. Dokter· 1 shared A. R. Decker-Farrell· 1 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. A. Amparo

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Author profile →

3 papers

Recent·Most cited

Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma

U. N. Wasko, J. Jiang, A. C. Garcia, Y. Wang, B. Lee, M. Orlen, K. Drizyte-Miller, M. Menard, J. Dilly, S. A. Sastra, C. F. Palermo, T. Dalton, M. C. Hasselluhn, A. R. Decker-Farrell, S. Chang, , R. H Vonderheide

This study evaluates the therapeutic potential of RMC-7977, a broad-spectrum RAS inhibitor, in pancreatic ductal adenocarcinoma models, showing strong anti-tumor effects with minimal impact on normal tissues.

bioRxiv · Dec 3, 2023 · PreprintCancer Biology

Bi-steric mTORC1-selective Inhibitors activate 4EBP1 reversing MYC-induced tumorigenesis and synergize with immunotherapy

W. D. Mahauad-Fernandez, Y. C. Yang, I. Lai, J. Park, L. Yao, J. W. Evans, G. L. Burnett, A. Gill, J. A. M. Smith, M. Singh, D. W. Felsher

This study identifies bi-steric mTORC1-selective inhibitors that reactivate 4EBP1, suppress MYC-driven tumors, and enhance immunotherapy in multiple cancer models.

bioRxiv · Feb 4, 2022 · PreprintCancer Biology

Unexpected diversity in socially synchronized rhythms of shorebirds

M. Bulla, M. Valcu, A. M. Dokter, A. A. Dondua, A. Kosztolanyi, A. Rutten, B. Helm, B. K. Sandercock, B. Casler, B. J. Ens, C. S. Spiegel, C. J. Hassell, C. Kupper, C. Minton, D. Burgas, , Koloski

This study examines incubation rhythms in shorebirds, finding significant diversity in synchronization patterns and linking them to predation risk rather than energy demands.

bioRxiv · Nov 23, 2016Animal Behavior & Cognition