Author

Y. C. Yang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. A. Germanos· 1 shared A. C. Hsieh· 1 shared A. G. Sowalsky· 1 shared A. Gill· 1 shared A. Long· 1 shared A. T. Ku· 1 shared C. M. Ghajar· 1 shared D. W. Felsher· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. A. Germanos

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Author profile →

2 papers

Recent·Most cited

Defining cellular population dynamics at single cell resolution during prostate cancer progression

A. A. Germanos, S. Arora, Y. Zheng, E. T. Goddard, I. M. Coleman, A. T. Ku, S. Wilkinson, R. A. Amezquita, M. Zager, A. Long, Y. C. Yang, J. H. Bielas, R. Gottardo, C. M. Ghajar, P. S. Nelson, , A. C. Hsieh

This study examines prostate cancer progression at single-cell resolution, identifying castration-resistant luminal cells and their role in treatment resistance and tumor heterogeneity.

bioRxiv · Mar 2, 2022Cancer Biology

Bi-steric mTORC1-selective Inhibitors activate 4EBP1 reversing MYC-induced tumorigenesis and synergize with immunotherapy

W. D. Mahauad-Fernandez, Y. C. Yang, I. Lai, J. Park, L. Yao, J. W. Evans, G. L. Burnett, A. Gill, J. A. M. Smith, M. Singh, D. W. Felsher

This study identifies bi-steric mTORC1-selective inhibitors that reactivate 4EBP1, suppress MYC-driven tumors, and enhance immunotherapy in multiple cancer models.

bioRxiv · Feb 4, 2022 · PreprintCancer Biology