Author

J. A. M. Y. Choo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

M. Dobbelstein· 2 shared A. Kleeberg· 1 shared A. Magerhans· 1 shared B. Wollnik· 1 shared D. Schloesser· 1 shared K. Stegmann· 1 shared M. Friedrich· 1 shared V. Manzini· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

M. Dobbelstein

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2 papers

Recent·Most cited

Cancer BiologybioRxivMar 11, 2020

The integrated stress response induces R-loops and hinders replication fork progression

J. A. M. Y. Choo, D. Schloesser, V. Manzini…·M. Dobbelstein

This paper shows that the integrated stress response (ISR) inhibits DNA replication by causing histone deficiency and R-loop formation, linking ISR to DNA replication regulation.

DOI 10.1038/s41419-020-2727-2

humanDNA methylation

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Cell BiologybioRxivPreprintJan 9, 2020

Centrosome impairment causes DNA replication stress through MLK3/MK2 signaling and R-loop formation

Z. Tayeh, K. Stegmann, A. Kleeberg…·M. Dobbelstein

DOI 10.1101/2020.01.09.898684

humanDNA methylation

𝕏 PostBluesky