Author

B. Wollnik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 6

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Research Focus:chromatin & epigenetic regulation· 3 Assay:DNA methylation· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

G. Hasenfuss· 2 shared G. Yigit· 2 shared Y. Li· 2 shared A. Hoischen· 1 shared A. Kleeberg· 1 shared A. M. Shah· 1 shared A. Maus· 1 shared A. Mirsaidi· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

G. Hasenfuss

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Author profile →

6 papers

Recent·Most cited

Reliability of high-quantity human brain organoids for modeling microcephaly, glioma invasion, and drug screening

A. Ramani, G. Pasquini, N. Gerkau, O. S. Vinchure, E. Gabriel, I. Rothenaigner, S. Lin, N. Altinisk, D. Rathinam, A. Mirsaidi, O. Goureau, L. Ricci-Vitiani, G. Q. d'alessandris, R. Pallini, B. Wollnik, , J. Gopalakrishnan

This study develops a high-throughput method to generate reliable human brain organoids for modeling microcephaly, glioma invasion, and drug screening.

bioRxiv · Oct 29, 2023Cell Biology

LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome

A. V. Busley, O. Gutierrez-Gutierrez, E. Hammer, F. Koitka, A. Mirzaiebadizi, M. Steinegger, C. Pape, L. Boehmer, H. Schroeder, M. Kleinsorge, M. Engler, I. C. Cirstea, L. Gremer, D. Willbold, J. Altmueller, , L. Cyganek

This study identifies a novel LZTR1 variant causing cardiac hypertrophy by altering protein polymerization and ubiquitin ligase function, showing genetic correction can rescue the phenotype.

bioRxiv · Jan 10, 2023Cell Biology

TRAIP regulates DNA double-strand break-induced ATM activation

T. Gleich, M. Quadroni, G. Yigit, B. Wollnik, M. Huber, C. Pich Bavastro, D. Hohl

This study identifies TRAIP as a novel regulator of ATM activation in response to DNA double-strand breaks, showing its role in maintaining ATM downstream targets and DNA repair.

bioRxiv · Oct 11, 2021 · PreprintCell Biology

Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients

L. Haupt, A. Maus, M. Tiburcy, S. Koehne, W. Maurer, R. Tappu, J. Haas, Y. Li, A. Sasse, C. Santos, R. Dressel, L. Wojnowski, G. Bunt, A. M. Shah, B. Meder, , K. Streckfuss-Bömeke

This study develops a human iPSC-CM model of DOX-induced cardiac dysfunction in B-cell lymphoma patients with high-dose DOX treatment, showing increased susceptibility to DOX toxicity and impaired mechanical function.

bioRxiv · Apr 15, 2020Cell Biology

Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology

Y. Kargapolova, R. Rehimi, H. Kayserli, J. Bruehl, A. Zirkel, Y. Li, G. Yigit, A. Hoischen, S. Frank, N. Russ, J. Trautwein, M. Laugsch, E. G. Gusmao, N. Josipovic, J. Altmeuller, , A. Papantonis

The paper identifies a CHD6 mutation causing Hallermann-Streiff syndrome and shows it disrupts autophagy and DNA damage response through chromatin remodeling.

bioRxiv · Jan 27, 2020Cell Biology

Centrosome impairment causes DNA replication stress through MLK3/MK2 signaling and R-loop formation

Z. Tayeh, K. Stegmann, A. Kleeberg, M. Friedrich, J. A. M. Y. Choo, B. Wollnik, M. Dobbelstein

bioRxiv · Jan 9, 2020 · PreprintCell Biology