Author

J. A. Steens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

R. H. J. Staals· 2 shared A. Shinkai· 1 shared B. J. F. Keijser· 1 shared B. Noordijk· 1 shared C. D. Schoen· 1 shared C. De Lannoy· 1 shared D. de Ridder· 1 shared D. Fuentenebro-Navas· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

R. H. J. Staals

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Nanopores reveal the stoichiometry of single oligo-adenylates produced by type III CRISPR-Cas

D. Fuentenebro-Navas, J. A. Steens, C. De Lannoy, B. Noordijk, D. de Ridder, R. H. J. Staals, S. Schmid

This study uses a nanopore assay with a CNN to detect and determine the stoichiometry of single cOAs produced by type III CRISPR-Cas systems.

bioRxiv · Aug 18, 2023 · PreprintBiophysics

SCOPE: Flexible targeting and stringent CARF activation enables type III CRISPR-Cas diagnostics

J. A. Steens, Y. Zhu, D. W. Taylor, J. P. K. Bravo, S. H. P. Prinsen, C. D. Schoen, B. J. F. Keijser, M. Ossendrijver, L. M. Hofstra, S. J. J. Brouns, A. Shinkai, J. van der Oost, R. H. J. Staals

This study identifies key regions in type III CRISPR-Cas systems for RNA targeting and cOA production, leading to the development of the SCOPE diagnostic tool for SARS-CoV-2 detection.

Nature Communications · Aug 19, 2021Peer-reviewedBiochemistry