Author

S. H. P. Prinsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

D. W. Taylor· 2 shared J. van der Oost· 2 shared A. Bardis· 1 shared A. Barendrecht· 1 shared A. M. Amieiro· 1 shared A. Shinkai· 1 shared B. J. F. Keijser· 1 shared C. D. Schoen· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

D. W. Taylor

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Author profile →

2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 23, 2023

Type III-B CRISPR-Cas signaling-based cascade of proteolytic cleavages

J. Steens, J. P. Bravo, C. R. P. Salazar…·R. Staals

This study characterizes a type III-B CRISPR-Cas system in Haliangium ochraceum, revealing a proteolytic cascade involving SAVED-CHAT and PCaspase that activates immune responses against RNA targets.

DOI 10.1101/2023.06.23.546230

bacteria (other)proteomics

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BiochemistryNature CommunicationsPeer-reviewedAug 19, 2021

SCOPE: Flexible targeting and stringent CARF activation enables type III CRISPR-Cas diagnostics

J. A. Steens, Y. Zhu, D. W. Taylor…·R. H. J. Staals

This study identifies key regions in type III CRISPR-Cas systems for RNA targeting and cOA production, leading to the development of the SCOPE diagnostic tool for SARS-CoV-2 detection.

DOI 10.1038/s41467-021-25337-5

humanexperimental assay

𝕏 PostBluesky