Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth
S. Gupta, J. A. Yano, H. Htwe Htwe, H. R. Shin, Z. Cakir, T. Ituarte, K. W. Wen, G. E. Kim, R. Zoncu, D. W. Dawson, R. M. Perera
This study identifies Myoferlin as a lysosomal membrane integrity factor in pancreatic cancer, showing its role in lysosome health and tumor growth.
Nature Cell Biology · Mar 8, 2021Peer-reviewedCancer Biology