Author

D. W. Dawson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

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Research Focus:cancer & tumor microenvironment· 4 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

A. J. Park· 1 shared A. M. Diaz· 1 shared A. Maker· 1 shared A. Rana· 1 shared A. Sattler· 1 shared C. C. DuFort· 1 shared C. Commisso· 1 shared C. Oon· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

A. J. Park

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4 papers

Recent·Most cited

Cell polarity proteins promote macropinocytosis in response to metabolic stress

G. Lambies, S.-W. Lee, K. Duong-Polk, P. Aza-Blanc, S. Maganti, D. W. Dawson, C. Commisso

This study identifies aPKC enzymes as regulators of macropinocytosis in PDAC cells under glutamine stress, showing their role in cell survival and tumor growth.

bioRxiv · Jan 16, 2024Cancer Biology

Mesenchymal Lineage Heterogeneity Underlies Non-Redundant Functions of Pancreatic Cancer-Associated Fibroblasts

E. J. Helms, M. W. Berry, R. C. Chaw, C. C. DuFort, D. Sun, M. K. Onate, C. Oon, S. Bhattacharyya, H. Sanford-Crane, W. Horton, J. M. Finan, A. Sattler, R. Makar, D. W. Dawson, Z. Xia, , M. H. Sherman

The paper identifies a minor subset of pancreatic cancer-associated fibroblasts (CAFs) derived from pancreatic stellate cells (PSCs) that have non-redundant functions in shaping the tumor microenvironment.

Cancer Discovery · Sep 21, 2021Peer-reviewedCancer Biology

Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth

S. Gupta, J. A. Yano, H. Htwe Htwe, H. R. Shin, Z. Cakir, T. Ituarte, K. W. Wen, G. E. Kim, R. Zoncu, D. W. Dawson, R. M. Perera

This study identifies Myoferlin as a lysosomal membrane integrity factor in pancreatic cancer, showing its role in lysosome health and tumor growth.

Nature Cell Biology · Mar 8, 2021Peer-reviewedCancer Biology

KRASG12D and TP53R167H Cooperate to Induce Pancreatic Ductal Adenocarcinoma in Sus Scrofa Pigs

D. R. Principe, N. H. Overgaard, A. J. Park, A. M. Diaz, C. Torres, R. McKinney, M. J. Dorman, K. Castellanos, R. Schwind, D. W. Dawson, A. Rana, A. Maker, H. G. Munshi, L. A. Rund, P. J. Grippo, L. B. Schook

This study creates a transgenic pig model of pancreatic ductal adenocarcinoma by expressing KRASG12D and TP53R167H, showing tumor development in vivo and providing a new large animal model for research.

bioRxiv · Jun 28, 2018Cancer Biology