Hydrogel-based slow release of a receptor-binding domain subunit vaccine elicits neutralizing antibody responses against SARS-CoV-2
E. C. Gale, A. E. Powell, G. A. Roth, E. L. Meany, J. Yan, B. S. Ou, A. K. Grosskopf, J. Adamska, V. C. T. M. Picece, A. I. d'Aquino, B. Pulendran, P. S. Kim, E. Appel
This study shows that slow release of an RBD subunit vaccine via hydrogel enhances neutralizing antibody responses against SARS-CoV-2 compared to bolus administration.
bioRxiv · Mar 31, 2021Bioengineering