Uncovering the ligandome of low-density lipoprotein receptor-related protein 1 in cartilage: a top-down approach to identify therapeutic targets
K. Yamamoto, C. Scavenius, M. M. Meschis, E. H. Mogensen, A. M. E. Gremida, I. B. Thogersen, S. Bonelli, S. D. Scilabra, S. Santamaria, J. Ahnström, G. Bou-Gharios, J. J. Enghild, H. Nagase
This study identifies the ligandome of LRP1 in cartilage using a top-down approach, revealing novel ligands and their role in osteoarthritis.
bioRxiv · Mar 2, 2022 · PreprintCell Biology