Author

J. Alvarado

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Cortes· 1 shared A. Kashyap· 1 shared A. Lauko· 1 shared A. Ortega· 1 shared A. P. Patel· 1 shared A. R. Carter· 1 shared A. Rojas· 1 shared A. Vera Kortmann· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

A. Cortes

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mendelian Randomization Analysis of the Relationship Between Native American Ancestry and Gallbladder Cancer Risk

L. Zollner, F. Boekstegers, C. Barahona Ponce, D. Scherer, K. Marcelain, V. Garate-Calderon, M. Waldenberger, E. Morales, A. Rojas, C. Munoz, B. Müller, J. Retamales, G. de Toro, A. Vera Kortmann, O. Barajas, , Ac

The paper uses Mendelian randomization to find a causal link between Mapuche ancestry and gallbladder cancer risk, with gallstone disease as a mediator.

medRxiv · May 3, 2022 · PreprintGenetic & Genomic Medicine

WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma

K. Mitchell, S. Shakya, S. Arora, S. A. Sprowls, D. J. Silver, C. M. Goins, L. Wallace, G. Roversi, R. Schafer, K. Kay, T. E. Miller, A. Lauko, A. Kashyap, J. D. Kass, E. E. Mulkearns-Hubert, , J. D. Lathia

This study identifies WDR5 as an essential epigenetic regulator in therapy-resistant glioblastoma cancer stem cells and shows that WDR5 inhibitors disrupt CSC maintenance and tumor growth.

bioRxiv · Sep 20, 2021Cancer Biology

Twinfilin1 controls lamellipodial protrusive activity and actin turnover during vertebrate gastrulation

C. Devitt, C. Lee, R. Cox, O. Papoulas, J. Alvarado, E. Marcotte, J. B. Wallingford

This study investigates the role of Twinfilin1 in actin dynamics during vertebrate gastrulation, linking it to lamellipodial protrusion and cell polarization.

bioRxiv · Sep 3, 2020Cell Biology