Author

O. Papoulas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Assay:cryo-EM· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. B. Wallingford· 5 shared C. Lee· 4 shared E. M. Marcotte· 4 shared C. L. McCafferty· 3 shared C. Devitt· 2 shared D. W. Taylor· 2 shared E. Marcotte· 2 shared R. Cox· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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5 shared papersCell Biology

J. B. Wallingford

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Author profile →

6 papers

Recent·Most cited

An amino acid-resolution interactome for motile cilia illuminates the structure and function of ciliopathy protein complexes

C. L. McCafferty, O. Papoulas, C. Lee, K. H. L. Bui, D. W. Taylor, E. M. Marcotte, J. B. Wallingford

The paper defines an amino acid-resolution interactome of motile cilia using XL/MS in Tetrahymena thermophila, revealing structural and functional insights into ciliary machines and ciliopathy proteins.

bioRxiv · Jul 9, 2023 · PreprintCell Biology

Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism

A. Ghanaeian, S. Majhi, C. L. McCafferty, B. Nami, C. S. Black, S. K. Yang, T. Legal, O. Papoulas, M. Janowska, M. Valente-Paterno, E. M. Marcotte, D. Wloga, K. H. Bui

The paper uses cryo-EM and integrative modeling to localize DRC subunits in the N-DRC of Tetrahymena thermophila and identifies interacting coiled-coil proteins.

bioRxiv · May 31, 2023Cell Biology

Label-free proteomic comparison reveals ciliary and non- ciliary phenotypes of IFT-A mutants

j. leggere, J. Hibbard, O. Papoulas, c. Lee, C. G. Pearson, E. M. Marcotte, J. B. Wallingford

The paper applies DIFFRAC to study proteomic changes in Ift122 mutants of Tetrahymena thermophila, revealing both ciliary and non-ciliary effects of IFT-A loss.

bioRxiv · Mar 8, 2023Cell Biology

Integrative modeling reveals the molecular architecture of the Intraflagellar Transport A (IFT-A) complex

C. L. McCafferty, O. Papoulas, M. A. Jordan, G. Hoogerbrugge, C. Nichols, G. Pigino, D. W. Taylor, J. B. Wallingford, E. M. Marcotte

The paper models the structure of the IFT-A complex using experimental and computational methods, revealing insights into ciliopathy-associated mutations.

bioRxiv · Jul 5, 2022Biochemistry

Twinfilin1 controls lamellipodial protrusive activity and actin turnover during vertebrate gastrulation

C. Devitt, C. Lee, R. Cox, O. Papoulas, J. Alvarado, E. Marcotte, J. B. Wallingford

This study investigates the role of Twinfilin1 in actin dynamics during vertebrate gastrulation, linking it to lamellipodial protrusion and cell polarization.

bioRxiv · Sep 3, 2020Cell Biology

Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins

C. Lee, R. Cox, O. Papoulas, A. Horani, K. Drew, C. Devitt, S. L. Brody, E. Marcotte, J. B. Wallingford

The paper shows that inner and outer dynein arm subunits are partitioned into non-overlapping regions within DynAPs and identifies Daap1 as a novel regulator of ODA deployment.

bioRxiv · Apr 21, 2020Cell Biology