Author

J. Anderl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Jennings· 1 shared C. J. Kirk· 1 shared C. Kalyanaraman· 1 shared C. Schroeter· 1 shared D. McMinn· 1 shared D. Schwarz· 1 shared D. Tranter· 1 shared E. Lowe· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Jennings

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Welding PROxAb Shuttles: A modular approach for generating bispecific antibodies via site-specific protein-protein conjugation

T. Lehmann, H. Schneider, J. Tonillo, J. Schanz, D. Schwarz, C. Schroeter, H. Kolmar, S. Hecht, J. Anderl, N. Rasche, M. Rieker, S. Dickgiesser

The paper describes a modular method to generate PROxAb Shuttles by conjugating PROTAC-binding VHHs to antibodies, enabling targeted protein degradation and bispecific antibody creation.

bioRxiv · Mar 15, 2024Biochemistry

Signal peptide mimicry primes Sec61 for client-selective inhibition

S. Rehan, D. Tranter, P. P. Sharp, E. Lowe, J. Anderl, T. Muchamuel, V. Abrishami, S. Kuivanen, N. Wenzell, A. Jennings, C. Kalyanaraman, G. B. Craven, T. Strandin, M. Javanainen, O. Vapalahti, , V. Paavilainen

This study describes KZR-8445, a cyclic depsipeptide that selectively inhibits Sec61-mediated protein biogenesis by mimicking signal peptides, showing efficacy in a rheumatoid arthritis model.

bioRxiv · Jul 3, 2022Biochemistry