Author

D. Schwarz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:protein sequence· 1

Frequent Co-Authors

C. Schroeter· 2 shared H. Schneider· 2 shared M. Rieker· 2 shared N. Rasche· 2 shared A. Evers· 1 shared A. K. Shalek· 1 shared A. Wegener· 1 shared B. S. Waldman· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

C. Schroeter

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Author profile →

3 papers

Recent·Most cited

Welding PROxAb Shuttles: A modular approach for generating bispecific antibodies via site-specific protein-protein conjugation

T. Lehmann, H. Schneider, J. Tonillo, J. Schanz, D. Schwarz, C. Schroeter, H. Kolmar, S. Hecht, J. Anderl, N. Rasche, M. Rieker, S. Dickgiesser

The paper describes a modular method to generate PROxAb Shuttles by conjugating PROTAC-binding VHHs to antibodies, enabling targeted protein degradation and bispecific antibody creation.

bioRxiv · Mar 15, 2024Biochemistry

PROxAb Shuttle: A non-covalent plug-and-play platform for the rapid generation of tumor-targeting antibody-PROTAC conjugates

H. Schneider, S. Jaeger, D. Koenning, N. Rasche, C. Schroeter, D. Elter, A. Evers, M. Lecomte, F. Riccardi Sirtori, D. Schwarz, A. Wegener, I. Hartung, M. Rieker

This paper introduces a platform for creating tumor-targeting antibody-PROTAC conjugates that enhances bioavailability and specificity without modifying PROTACs or antibodies.

bioRxiv · Sep 29, 2023 · PreprintBiochemistry

Identification of a master regulator of differentiation in Toxoplasma

B. S. Waldman, D. Schwarz, M. H. Wadsworth, J. P. J. Saeij, A. K. Shalek, S. Lourido

This study identifies BFD1 as a master regulator of differentiation in Toxoplasma gondii through genetic screening and single-cell profiling, showing its necessity and sufficiency for the transition from tachyzoites to bradyzoites.

bioRxiv · Jun 5, 2019Microbiology