Author

J. Arnsdorf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

N. E. Lewis· 2 shared S. Schoffelen· 2 shared A. G. Peralta· 1 shared A. H. Hansen· 1 shared A. W. Chiang· 1 shared A. W. T. Chiang· 1 shared B. Choudhury· 1 shared B. G. R. Voldborg· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

N. E. Lewis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LeGenD: determining N-glycoprofiles using an explainable AI-leveraged model with lectin profiling

H. Li, A. G. Peralta, S. Schoffelen, A. H. Hansen, J. Arnsdorf, S.-M. Schinn, J. Skidmore, B. Choudhury, M. Paulchakrabarti, B. G. Voldborg, A. W. T. Chiang, N. E. Lewis

LeGenD predicts N-glycan structures and their abundance using lectin-binding patterns and AI, trained on glycoprofiles from recombinant proteins.

bioRxiv · Mar 27, 2024 · PreprintBioengineering

Glycoengineered recombinant alpha1-antitrypsin results in comparable in vitro and in vivo activities to human plasma-derived protein

F. Rocamora, S. Schoffelen, J. Arnsdorf, E. A. Toth, Y. Abdul, T. E. Cleveland, S. P. Bjorn, M. Y. M. Wu, N. G. McElvaney, B. G. R. Voldborg, T. R. Fuerst, N. E. Lewis

This study generates glycoengineered recombinant alpha1-antitrypsin with in vitro and in vivo activities comparable to plasma-derived A1AT, offering a sustainable therapeutic alternative.

bioRxiv · Mar 27, 2024 · PreprintBioengineering

Multiplex secretome engineering enhances recombinant protein production and purity

S. Kol, D. Ley, T. Wulff, M. Decker, J. Arnsdorf, J. M. Gutierrez, A. W. Chiang, L. E. Pedersen, H. F. Kildegaard, G. M. Lee, N. Lewis

This study shows that deleting multiple host cell proteins in CHO cells improves recombinant protein production and purity through enhanced purification efficiency.

bioRxiv · May 24, 2019Bioengineering