Author

B. Choudhury

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Evolutionary Biology· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 6 Assay:metagenomics· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

E. Luna· 2 shared G. E. Flores· 2 shared L. Padilla· 2 shared M. Paulchakrabarti· 2 shared A. D. Fricker· 1 shared A. G. Peralta· 1 shared A. H. Hansen· 1 shared A. J. Klingelhutz· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

E. Luna

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

A sneak peek at the high altitude adaptation of the Ladakh populations

U. Chorol, B. Choudhury, T. Norboo, N. P. Wangchuk, G. Chaubey, C. Basu

This study examines physiological and genetic adaptations of Ladakh populations to high altitude, finding correlations between haemoglobin levels, lipid profiles, and regional altitude.

bioRxiv · Mar 31, 2024 · PreprintEvolutionary Biology

LeGenD: determining N-glycoprofiles using an explainable AI-leveraged model with lectin profiling

H. Li, A. G. Peralta, S. Schoffelen, A. H. Hansen, J. Arnsdorf, S.-M. Schinn, J. Skidmore, B. Choudhury, M. Paulchakrabarti, B. G. Voldborg, A. W. T. Chiang, N. E. Lewis

LeGenD predicts N-glycan structures and their abundance using lectin-binding patterns and AI, trained on glycoprofiles from recombinant proteins.

bioRxiv · Mar 27, 2024 · PreprintBioengineering

Mechanism of 2-Fucosyllactose degradation by Human-Associated Akkermansia

A. D. Fricker, L. Padilla, E. Luna, B. Choudhury, E. R. Hughes, M. E. Panzetta, R. Valdivia, G. E. Flores

The paper identifies fucosidase and β-galactosidase genes in Akkermansia species responsible for 2-FL degradation, showing their role in bacterial growth and gut microbiota development.

bioRxiv · Oct 17, 2023 · PreprintMicrobiology

Phased assembly of neo-sex chromosomes reveals extensive Y degeneration and rapid genome evolution in Rumex hastatulus

B. M. Sacchi, Z. Humphries, J. Kruzlicova, M. Bodlakova, C. Pyne, B. Choudhury, Y. Gong, V. Bacovsky, R. Hobza, S. C. H. Barrett, S. I. Wright

The paper studies Y chromosome degeneration in Rumex hastatulus by analyzing phased genome assemblies of old and new sex chromosomes, finding extensive gene loss and transposable element expansion on the Y chromosome.

bioRxiv · Sep 26, 2023 · PreprintEvolutionary Biology

B3GALT6 Promotes Dormant Breast Cancer Cell Survival and Recurrence by Enabling Heparan Sulfate-Mediated FGF Signaling

A. Sreekumar, M. Lu, B. Choudhury, T.-c. Pan, D. K. Pant, C. J. Sterner, G. K. Belka, T. Toriumi, B. Benz, M. Escobar-Aguirre, F. E. Marino, J. D. Esko, L. A. Chodosh

The paper identifies B3GALT6 as a key regulator of dormant breast cancer cell survival and recurrence through heparan sulfate-mediated FGF signaling.

bioRxiv · Jan 31, 2023Cancer Biology

Distributed Compact Plasma Reactor Sterilization for Planetary Protection in Space Missions

B. Choudhury, T. Revazishvili, S. Roy, M. Lozada, S. Roy, E. Mastro, S. Portugal

This study demonstrates the effectiveness of the Active Plasma Sterilizer (APS) in achieving log reductions of pathogenic bacteria on various materials using cold plasma technology.

bioRxiv · Nov 14, 2022 · PreprintMicrobiology

Avian and Human Influenza Viruses Exhibit Distinct Glycoconjugate Receptor Specificities in Human Lung Cells

C.-Y. Liang, I. Huang, J. Han, S. Manivasagam, J. Plung, M. Sturtz, Y. Yu, M. Kandasamy, F. A. Gourronc, A. J. Klingelhutz, B. Choudhury, L. Rong, J. T. Perez, S. Neelamegham, B. Manicassamy

The paper shows human and avian influenza viruses use different glycoconjugate types for infection, with avian strains using a broader range.

bioRxiv · Jun 29, 2022Microbiology

Utilization efficiency of human milk oligosaccharides by human-associated Akkermansia is strain-dependent

E. Luna, S. G. Parkar, N. Kirmiz, S. Hartel, E. Hearn, M. Hossine, A. Kurdian, C. Mendoza, K. Orr, L. Padilla, K. Ramirez, P. Salcedo, E. Serrano, B. Choudhury, M. Paulchakrabarti, , G. E. Flores

This study examines how different Akkermansia strains utilize human milk oligosaccharides (HMOs) with varying efficiency, showing strain-dependent growth and metabolite production.

bioRxiv · Jul 26, 2021Microbiology

Mucin-derived O-glycans supplemented to diet mitigate diverse microbiota perturbations

K. M. Pruss, A. Marcobal, A. Southwick, D. Dahan, S. Smits, J. Ferreyra, S. Higginbottom, E. Sonnenburg, P. Kashyap, B. Choudhury, L. Bode, J. Sonnenburg

The paper shows that mucin-derived O-glycans can restore microbiota balance and improve host health by promoting beneficial microbes and suppressing pathogens.

bioRxiv · Jun 9, 2020Microbiology