Complex structural variation is prevalent and highly pathogenic in pediatric solid tumors
I. A. E. M. van Belzen, M. C. van Tuil, S. Badloe, A. Janse, E. T. P. Verwiel, M. Santoso, S. de Vos, J. Baker-Hernandez, H. H. D. Kerstens, N. Solleveld-Westerink, M. T. Meister, J. Drost, M. M. van den Heuvel-Eibrink, J. H. M. Merks, J. J. Molenaar, , J. Y. Hehir-Kwa
The paper identifies prevalent and pathogenic complex structural variations in pediatric solid tumors, linking them to adverse clinical outcomes and potential therapeutic targets.
bioRxiv · Sep 19, 2023Cancer Biology